Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
Department of Health and Human Services
The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. This NOFO will utilize the UG3/UH3 activity code.
Funding
Award size
$1M – $10M
Award ceiling
3000000
Type
Cooperative Agreement
Dates
Deadline
Later
Posted
09/10/2025
Closes
2028-08-21
Eligibility
Eligibility
Independent school districtsNonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationPrivate institutions of higher educationCity or township governmentsFor profit organizations other than small businessesOthers (see text field entitled "Additional Information on Eligibility" for clarification)Public housing authorities/Indian housing authoritiesPublic and State controlled institutions of higher educationState governmentsSpecial district governmentsNonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher educationSmall businessesNative American tribal organizations (other than Federally recognized tribal governments)Native American tribal governments (Federally recognized)County governments
Program
Funding area
Education - EDHealth - HL
Opportunity #
PAR-25-446
Source
Status
Open
Market
Government
Level
Federal
Source
Grants.gov