Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
Department of Health and Human Services
This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of clinical projects that address critical needs for clinical trial readiness in rare diseases. The initiative seeks applications that are intended to facilitate rare diseases research by enabling efficient and effective movement of candidate therapeutics or diagnostics toward clinical trials, and to increase their likelihood of success. This could be through the development and testing of rigorous biomarkers and clinical outcome assessment measures, or by defining the presentation and course of a rare disease to enable the design of upcoming clinical trials.
Funding
Award size
Not specified
Type
Grant
Dates
Deadline
Later
Posted
09/22/2025
Closes
2028-07-20
Eligibility
Eligibility
Private institutions of higher educationNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationCounty governmentsOthers (see text field entitled "Additional Information on Eligibility" for clarification)Special district governmentsNonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher educationFor profit organizations other than small businessesIndependent school districtsPublic and State controlled institutions of higher educationSmall businessesCity or township governmentsPublic housing authorities/Indian housing authoritiesState governmentsNative American tribal governments (Federally recognized)
Program
Funding area
Health - HLIncome Security and Social Services - ISS
Opportunity #
PAR-25-450
Source
Status
Open
Market
Government
Level
Federal
Source
Grants.gov