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Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)

Department of Health and Human Services

The purpose of this Notice of Funding Opportunity (NOFO) is to fund clinical trials of products evaluating efficacy and/or safety in support of a new indication or change in labeling to address unmet needs in rare diseases or conditions. Additionally, through the funding of collaborative, efficient, and/or innovative clinical trials, FDA expects to increase the number of approved treatments for rare diseases and exert a broad and positive impact on rare disease drug development.

Funding

Award size
$100K – $1M
Award ceiling
900000
Type
Grant

Dates

Deadline
Later
Posted
07/11/2025
Closes
2028-05-16

Eligibility

Eligibility
Others (see text field entitled "Additional Information on Eligibility" for clarification)

Program

Funding area
Agriculture - AGConsumer Protection - CPFood and Nutrition - FN
Opportunity #
RFA-FD-25-020

Source

Status
Open
Market
Government
Level
Federal
Source
Grants.gov

Contact

Contact email
Contact phone

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